Synthesis of New Macrocyclic Polyamides as Antimicrobial Agent Candidates

Synthesis of New Macrocyclic Polyamides as Antimicrobial Agent Candidates

A series of macrocyclic imides and Schiff-bases have been prepared via the cyclocondensation of pyridine-2,6-dicarbonyl dichloride (1) with L-ornithine methyl ester to give the corresponding macrocyclic bisester 2. Treatment of 2 with hydrazine hydrate gave macrocyclic bisacid hydrazide 3, which was...

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Bibliographic Details
Main Authors: Osama I. Abd El-Salam, Mohamed A. Al-Omar, Ahmed A. Fayed, Eman M. Flefel, Abd El-Galil E. Amr
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Molecules
Subjects:
macrocyclic polyamide candidates
amino acids
Schiff&#8217
s base
antimicrobial activity
Online Access:http://www.mdpi.com/1420-3049/17/12/14510

Internet

http://www.mdpi.com/1420-3049/17/12/14510

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