Functional analysis of OCTN2 and ATB0,+ in normal human airway epithelial cells.

In human, OCTN2 (SLC22A5) and ATB0,+ (SLC6A14) transporters mediate the uptake of L-carnitine, essential for the transport of fatty acids into mitochondria and the subsequent degradation by β-oxidation. Aim of the present study was to characterize L-carnitine transport in EpiAirway™, a 3D organotypi...

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Bibliographic Details
Main Authors: Bianca Maria Rotoli, Rossana Visigalli, Amelia Barilli, Francesca Ferrari, Massimiliano G Bianchi, Maria Di Lascia, Benedetta Riccardi, Paola Puccini, Valeria Dall'Asta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228568