Thermosensitive Bioadhesive Hydrogels Based on Poly(<i>N</i>-isopropylacrilamide) and Poly(methyl vinyl ether-<i>alt</i>-maleic anhydride) for the Controlled Release of Metronidazole in the Vaginal Environment

Thermosensitive Bioadhesive Hydrogels Based on Poly(<i>N</i>-isopropylacrilamide) and Poly(methyl vinyl ether-<i>alt</i>-maleic anhydride) for the Controlled Release of Metronidazole in the Vaginal Environment

The development of thermosensitive bioadhesive hydrogels as multifunctional platforms for the controlled delivery of microbicides is a valuable contribution for the in situ treatment of vagina infections. In this work, novel semi-interpenetrating network (s-IPN) hydrogels were prepared by the entrap...

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Bibliographic Details
Main Authors: Ana V. Torres-Figueroa, Cinthia J. Pérez-Martínez, J. Carmelo Encinas, Silvia Burruel-Ibarra, María I. Silvas-García, Alejandro M. García Alegría, Teresa del Castillo-Castro
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
nanocomposite hydrogel
thermosensitive hydrogel
bioadhesive hydrogel
controlled drug release
metronidazole
Online Access:https://www.mdpi.com/1999-4923/13/8/1284

Internet

https://www.mdpi.com/1999-4923/13/8/1284

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