Metabolic regulation of mycobacterial growth and antibiotic sensitivity.

Treatment of chronic bacterial infections, such as tuberculosis (TB), requires a remarkably long course of therapy, despite the availability of drugs that are rapidly bacteriocidal in vitro. This observation has long been attributed to the presence of bacterial populations in the host that are "...

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Bibliographic Details
Main Authors: Seung-Hun Baek, Alice H Li, Christopher M Sassetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3101192?pdf=render