miR-195 inhibits macrophages pro-inflammatory profile and impacts the crosstalk with smooth muscle cells.

miR-195 inhibits macrophages pro-inflammatory profile and impacts the crosstalk with smooth muscle cells.

Macrophages are a main component of atherosclerotic plaques. Recent studies suggest that pro-inflammatory M1 macrophages are pro-atherogenic while M2 macrophages promote plaque stability. Moreover, toll-like receptor signalling pathways are implicated in atherosclerotic plaque formation, evolution a...

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Bibliographic Details
Main Authors: Joao Paulo Bras, Andreia Machado Silva, George A Calin, Mario Adolfo Barbosa, Susana Gomes Santos, Maria Ines Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5699821?pdf=render

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http://europepmc.org/articles/PMC5699821?pdf=render

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