Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm.
<h4>Background</h4>Male-factor infertility is a common condition, and etiology is unknown for a high proportion of cases. Abnormal epigenetic programming of the germline is proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infer...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-12-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0001289 |