Clonal evolution and progression of 20-methylcholanthrene-induced squamous cell carcinoma of mouse epidermis as revealed by DNA instability and other malignancy markers
We examined the clonal evolution of skin malignant lesions by repeated topical applications of 20- methylcholanthrene (20-MC) to the skin, which induces hyperplastic epidermis, papillomatous lesion and invasive carcinoma in mice. The lesions were examined histologically and immunohistochemically wit...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2009-12-01
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Series: | European Journal of Histochemistry |
Online Access: | https://www.ejh.it/index.php/ejh/article/view/1641 |