DNA aptamer-based rolling circle amplification product as a novel immunological adjuvant

DNA aptamer-based rolling circle amplification product as a novel immunological adjuvant

Abstract Several agonists to CD40 have shown to induce acquired immune responses. Here, we developed and evaluated the rolling circle amplification (RCA) products that are based on anti-CD40 DNA aptamers as a novel vaccine adjuvant. First, we developed DNA aptamers with specific binding affinity to...

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Bibliographic Details
Main Authors: Adil S. Al-Ogaili, Rohana Liyanage, Jack O. Lay, Tieshan Jiang, Christine N. Vuong, Shilpi Agrawal, Thallapuranam Krishnaswamy Suresh Kumar, Luc R. Berghman, Billy M. Hargis, Young Min Kwon
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79420-w

Internet

https://doi.org/10.1038/s41598-020-79420-w

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