Enantioselective Synthesis of Chromanones Bearing an α,α-Disubstituted α-Amino Acid Moiety via Decarboxylative Michael Reaction

In this manuscript, a novel, decarboxylative Michael reaction between α-substituted azlactones and chromone-3-carboxylic acids is described. The reaction proceeds in a sequence Michael addition followed by decarboxylative deprotonation, and it results in the formation of chromanones bearing...

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Bibliographic Details
Main Authors: Jan Bojanowski, Lesław Sieroń, Anna Albrecht
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/14/2565