Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria

Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria

To address the impact of microbiome on disease development, it is essential to go beyond a descriptive study and evaluate the physiological importance of microbiome changes. Our study integrates computational analysis with in vitro and in vivo exploration of inflammatory properties of spore-forming...

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Bibliographic Details
Main Authors: Egle Cekanaviciute, Anne-Katrin Pröbstel, Anna Thomann, Tessel F. Runia, Patrizia Casaccia, Ilana Katz Sand, Elizabeth Crabtree, Sneha Singh, John Morrissey, Patrick Barba, Refujia Gomez, Rob Knight, Sarkis Mazmanian, Jennifer Graves, Bruce A. C. Cree, Scott S. Zamvil, Sergio E. Baranzini
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mSystems
Subjects:
immune mechanisms
multiple sclerosis
spore-forming bacteria
Online Access:https://doi.org/10.1128/mSystems.00083-18

Internet

https://doi.org/10.1128/mSystems.00083-18

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