The DnaK Chaperone Uses Different Mechanisms To Promote and Inhibit Replication of Vibrio cholerae Chromosome 2
Replication of Vibrio cholerae chromosome 2 (Chr2) depends on molecular chaperone DnaK to facilitate binding of the initiator (RctB) to the replication origin. The binding occurs at two kinds of site, 12-mers and 39-mers, which promote and inhibit replication, respectively. Here we show that DnaK em...
Main Authors: | Jyoti K. Jha, Mi Li, Rodolfo Ghirlando, Lisa M. Miller Jenkins, Alexander Wlodawer, Dhruba Chattoraj, Gary M. Dunny |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-04-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/2/e00427-17 |
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