Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data

Ub-ISAP: a streamlined UNIX pipeline for mining unique viral vector integration sites from next generation sequencing data

Abstract Background The analysis of viral vector genomic integration sites is an important component in assessing the safety and efficiency of patient treatment using gene therapy. Alongside this clinical application, integration site identification is a key step in the genetic mapping of viral elem...

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Bibliographic Details
Main Authors: Atul Kamboj, Claus V. Hallwirth, Ian E. Alexander, Geoffrey B. McCowage, Belinda Kramer
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Bioinformatics
Subjects:
Gene therapy
Integration site analysis
Next-generation sequencing
Viral vectors
Online Access:http://link.springer.com/article/10.1186/s12859-017-1719-4

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http://link.springer.com/article/10.1186/s12859-017-1719-4

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