Activation of hepatic estrogen receptor-α increases energy expenditure by stimulating the production of fibroblast growth factor 21 in female mice

Activation of hepatic estrogen receptor-α increases energy expenditure by stimulating the production of fibroblast growth factor 21 in female mice

Objective: The endogenous estrogen 17β-estradiol (E2) promotes metabolic homeostasis in premenopausal women. In a mouse model of post-menopausal metabolic syndrome, we reported that estrogens increased energy expenditure, thus preventing estrogen deficiency-induced adiposity. Estrogens' prevent...

Full description

Bibliographic Details
Main Authors: Camille Allard, Fabrice Bonnet, Beibei Xu, Laurel Coons, Diana Albarado, Cristal Hill, Guy Fagherazzi, Kenneth S. Korach, Ellis R. Levin, John Lefante, Christopher Morrison, Franck Mauvais-Jarvis
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781831202X

Internet

http://www.sciencedirect.com/science/article/pii/S221287781831202X

Similar Items