Pharmacological treatments inhibiting levodopa-induced dyskinesias in MPTP-lesioned monkeys: brain glutamate biochemical correlates

Antiglutamatergic drugs can relieve Parkinson’s disease (PD) symptoms and decrease L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias (LID). This review reports relevant studies investigating glutamate receptor subtypes in relation to motor complications in PD patients and 1-methyl-4-phenyl-1...

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Bibliographic Details
Main Authors: Nicolas eMorin, Thérèse eDi Paolo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00144/full