A genome-wide positioning systems network algorithm for in silico drug repurposing

A genome-wide positioning systems network algorithm for in silico drug repurposing

Identification of disease modules in the human interactome can guide more efficacious therapeutic selections. Here, the authors introduce a network-based methodology to identify individualized disease modules by mapping patients’ DNA and RNA sequencing profiles to the interactome, enabling predictio...

Full description

Bibliographic Details
Main Authors: Feixiong Cheng, Weiqiang Lu, Chuang Liu, Jiansong Fang, Yuan Hou, Diane E. Handy, Ruisheng Wang, Yuzheng Zhao, Yi Yang, Jin Huang, David E. Hill, Marc Vidal, Charis Eng, Joseph Loscalzo
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10744-6

Internet

https://doi.org/10.1038/s41467-019-10744-6

Similar Items