Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy.

Members of the vascular endothelial growth factor (VEGF) family of proteins are critical regulators of angiogenesis. VEGF concentration gradients are important for activation and chemotactic guidance of capillary sprouting, but measurement of these gradients in vivo is not currently possible. We hav...

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Bibliographic Details
Main Authors: Feilim Mac Gabhann, James W Ji, Aleksander S Popel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1570371?pdf=render