CpG islands undermethylation in human genomic regions under selective pressure.

DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential. DNA methylation is involved also in several processes that are central to evolutionary biology, including pheno...

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Bibliographic Details
Main Authors: Sergio Cocozza, Most Mauluda Akhtar, Gennaro Miele, Antonella Monticelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149076?pdf=render