Investigation of the three-dimensional lattice HP protein folding model using a genetic algorithm

An approach to the hydrophobic-polar (HP) protein folding model was developed using a genetic algorithm (GA) to find the optimal structures on a 3D cubic lattice. A modification was introduced to the scoring system of the original model to improve the model's capacity to generate more natural-l...

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Bibliographic Details
Main Authors: Fábio L. Custódio, Hélio J. C. Barbosa, Laurent E. Dardenne
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2004-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400023