Prolonged, brain-wide expression of nuclear-localized GCaMP3 for functional circuit mapping

Prolonged, brain-wide expression of nuclear-localized GCaMP3 for functional circuit mapping

Larval zebrafish offer the potential for large-scale optical imaging of neural activity throughout the central nervous system; however, several barriers challenge their utility. First, ~panneuronal probe expression has to date only been demonstrated at early larval stages up to 7 days post-fertiliza...

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Bibliographic Details
Main Authors: Christina Kay Kim, Andrew eMiri, Louis eLeung, Andre eBerndt, Philippe eMourrain, David W. Tank, Rebecca D. Burdine
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Neural Circuits
Subjects:
genetically encoded calcium indicators
in vivo calcium imaging
transgenic zebrafish
nuclear calcium signals
brain-wide expression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00138/full

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http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00138/full

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