Intracellular regulation of cross-presentation during dendritic cell maturation.

We have investigated the effect of different maturation stimuli on the ability of mature dendritic cells (DCs) to cross-present newly acquired particulate antigens. Cross-presentation was impaired in DCs matured by treatment with TNF-α, CpG and LPS, but was less affected upon CD40L-induced maturatio...

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Bibliographic Details
Main Authors: Claudia S Wagner, Jeff Grotzke, Peter Cresswell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789698?pdf=render