Inhibition of connexin 43 attenuates oxidative stress and apoptosis in human umbilical vein endothelial cells

Inhibition of connexin 43 attenuates oxidative stress and apoptosis in human umbilical vein endothelial cells

Abstract Background Previous studies demonstrated an important role for connexin 43 (Cx43) in the regulation of apoptosis by influencing mitochondrial functions. This study aimed to investigate the relationship between Cx43 and lipopolysaccharide (LPS)-induced oxidative stress and apoptosis in human...

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Bibliographic Details
Main Authors: Jia-wei Ma, Dan-dan Ji, Qian-qian Li, Ting Zhang, Liang Luo
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Pulmonary Medicine
Subjects:
Acute respiratory distress syndrome
Endothelial cell
Mitochondrion
Connexin 43
Lipopolysaccharides
Oxidative stress
Online Access:https://doi.org/10.1186/s12890-019-1036-y

Internet

https://doi.org/10.1186/s12890-019-1036-y

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