Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway

Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway

Background: Diabetic nephropathy (DN) is a serious complication of diabetes mellitus and a common cause of end-stage renal disease. Autophagy has a defensive role against kidney damage caused by hyperglycemia. Mesenchymal stem cell (MSC)-derived exosomes are currently considered as a new promising t...

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Bibliographic Details
Main Authors: Nesrine Ebrahim, Inas A. Ahmed, Noha I. Hussien, Arigue A. Dessouky, Ayman Samir Farid, Amal M. Elshazly, Ola Mostafa, Walaa Bayoumie El Gazzar, Safwa M. Sorour, Yasmin Seleem, Ahmed M. Hussein, Dina Sabry
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
diabetic nephropathy
exosomes
autophagy
mTOR
Online Access:https://www.mdpi.com/2073-4409/7/12/226

Internet

https://www.mdpi.com/2073-4409/7/12/226

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