Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.

Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.

The purpose of this study is to assess the preclinical therapeutic efficacy of magnetic resonance imaging (MRI)-monitored focused ultrasound (FUS)-induced blood-brain barrier (BBB) disruption to enhance Temozolomide (TMZ) delivery for improving Glioblastoma Multiforme (GBM) treatment. MRI-monitored...

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Bibliographic Details
Main Authors: Kuo-Chen Wei, Po-Chun Chu, Hay-Yan Jack Wang, Chiung-Yin Huang, Pin-Yuan Chen, Hong-Chieh Tsai, Yu-Jen Lu, Pei-Yun Lee, I-Chou Tseng, Li-Ying Feng, Peng-Wei Hsu, Tzu-Chen Yen, Hao-Li Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602591?pdf=render

Internet

http://europepmc.org/articles/PMC3602591?pdf=render

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