Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells

<p>Abstract</p> <p>Background</p> <p>Excessive production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. Previous studies have...

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Bibliographic Details
Main Authors: Zhang Yumin, Ribeiro Rachel, Wen Jie
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/38