Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells
<p>Abstract</p> <p>Background</p> <p>Excessive production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. Previous studies have...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-04-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/8/1/38 |