Core–shell nanoparticles suppress metastasis and modify the tumour-supportive activity of cancer-associated fibroblasts

Core–shell nanoparticles suppress metastasis and modify the tumour-supportive activity of cancer-associated fibroblasts

Abstract Background Although accumulating evidence suggests that the crosstalk between malignant cells and cancer-associated fibroblasts (CAFs) actively contributes to tumour growth and metastatic dissemination, therapeutic strategies targeting tumour stroma are still not common in the clinical prac...

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Bibliographic Details
Main Authors: Dávid Kovács, Nóra Igaz, Annamária Marton, Andrea Rónavári, Péter Bélteky, László Bodai, Gabriella Spengler, László Tiszlavicz, Zsolt Rázga, Péter Hegyi, Csaba Vizler, Imre M. Boros, Zoltán Kónya, Mónika Kiricsi
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Nanobiotechnology
Subjects:
Core–shell nanoparticles
Tumour stroma
Cancer-associated fibroblasts
Metastasis
RNA sequencing
Online Access:https://doi.org/10.1186/s12951-020-0576-x

Internet

https://doi.org/10.1186/s12951-020-0576-x

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