Distinct phosphorylation requirements regulate cortactin activation by Tir<sub>EPEC </sub>and its binding to N-WASP
<p>Abstract</p> <p>Background</p> <p>Cortactin activates the actin-related 2/3 (Arp2/3) complex promoting actin polymerization to remodel cell architecture in multiple processes (e.g. cell migration, membrane trafficking, invadopodia formation etc.). Moreover, it was ca...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-05-01
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Series: | Cell Communication and Signaling |
Online Access: | http://www.biosignaling.com/content/7/1/11 |