Distinct phosphorylation requirements regulate cortactin activation by Tir<sub>EPEC </sub>and its binding to N-WASP

<p>Abstract</p> <p>Background</p> <p>Cortactin activates the actin-related 2/3 (Arp2/3) complex promoting actin polymerization to remodel cell architecture in multiple processes (e.g. cell migration, membrane trafficking, invadopodia formation etc.). Moreover, it was ca...

Full description

Bibliographic Details
Main Authors: Martinez-Quiles Narcisa, Nieto-Pelegrin Elvira
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Cell Communication and Signaling
Online Access:http://www.biosignaling.com/content/7/1/11