Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies

<p>Abstract</p> <p>Background</p> <p>Phenotype error causes reduction in power to detect genetic association. We present a quantification of phenotype error, also known as diagnostic error, on power and sample size calculations for case-control genetic association studi...

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Bibliographic Details
Main Authors: Finch Stephen J, Levenstien Mark A, Haynes Chad, Edwards Brian J, Gordon Derek
Format: Article
Language:English
Published: BMC 2005-04-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/6/18