High Cytoplasmic CXCR4 Expression Predicts Prolonged Survival in Triple-Negative Breast Cancer Patients Treated with Adjuvant Chemotherapy

Background Chemokine receptor CXC chemokine receptor type 4 (CXCR4) and its ligand CXC motif chemokine 12 (CXCL12; stromal cell-derived factor-1) are implicated in tumor growth, metastasis, and tumor cell-microenvironment interaction. A number of studies have reported that increased CXCR4 expression...

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Bibliographic Details
Main Authors: Bobae Shim, Min-Sun Jin, Ji Hye Moon, In Ae Park, Han Suk Ryu
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2018-11-01
Series:Journal of Pathology and Translational Medicine
Subjects:
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2018-09-19.pdf