Chemokine CXCL13 as a New Systemic Biomarker for B-Cell Involvement in Acute T Cell-Mediated Kidney Allograft Rejection

Chemokine CXCL13 as a New Systemic Biomarker for B-Cell Involvement in Acute T Cell-Mediated Kidney Allograft Rejection

The presence of B-cell clusters in allogenic T cell-mediated rejection (TCMR) of kidney allografts is linked to more severe disease entities. In this study we characterized B-cell infiltrates in patients with TCMR and examined the role of serum CXCL-13 in these patients and experimentally. CXCL-13 s...

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Bibliographic Details
Main Authors: Lena Schiffer, Flavia Wiehler, Jan Hinrich Bräsen, Wilfried Gwinner, Robert Greite, Kirill Kreimann, Anja Thorenz, Katja Derlin, Beina Teng, Song Rong, Sibylle von Vietinghoff, Hermann Haller, Michael Mengel, Lars Pape, Christian Lerch, Mario Schiffer, Faikah Gueler
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
B-cell attracting chemokine
CXCL13
kidney transplantation
allograft rejection
T cell-mediated rejection
Online Access:https://www.mdpi.com/1422-0067/20/10/2552

Internet

https://www.mdpi.com/1422-0067/20/10/2552

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