Klebsiella pneumoniae: development of carbapenem resistance due to acquisition of blaNDM-1 during antimicrobial therapy in twin infants with pneumonia

Objectives: To identify the mechanism of in vivo development of carbapenem resistance in Klebsiella pneumoniae.Methods: Seven sequential isolates of K. pneumoniae were obtained from twin infants with pneumonia. Antimicrobial susceptibility testing was performed by agar dilution. Carbapenemases inclu...

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Bibliographic Details
Main Authors: Junying eZhu, Baixing eDing, Xiaogang eXu, Demei eZhu, fan eYang, Hong eZhang, Fupin eHu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01399/full