NHC-Catalyzed Organocatalytic Asymmetric Approach to 2,2-Disubstituted Benzofuran-3(2<i>H</i>)-ones Containing Fully Substituted Quaternary Stereogenic Center
A highly efficient and enantioselective approach to the synthesis of functionalized benzofuran-3(2<i>H</i>)-ones is presented. It proceeds via an intramolecular Stetter reaction using β,β-disubstituted Michael acceptors in the construction of five-membered rings with fu...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-02-01
|
Series: | Catalysts |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4344/9/2/192 |