The Invisible Threat of Non-steroidal Anti-inflammatory Drugs for Kidneys

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are often used as analgesic and antipyretic drugs. Nephrotoxicity is a common side effect and leads in 1–5% of pediatric cases to acute kidney injury (AKI). The nephrotoxic effects of NSAIDs arise mainly from two pathological mechanisms: (1)...

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Bibliographic Details
Main Authors: Stéphanie Clavé, Caroline Rousset-Rouvière, Laurent Daniel, Michel Tsimaratos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00520/full