Isolation, analysis and in vitro assessment of CYP3A4 inhibition by methylxanthines extracted from Pu-erh and Bancha tea leaves
Abstract Methylxanthines, purine alkaloids found in plants, are found in beverages (coffee, tea, cocoa) and foods (chocolate and other cocoa-containing foods) commonly consumed worldwide. Members of this family include caffeine, theophylline and theobromine. Methylxanthines have a variety of pharmac...
Main Authors: | Kaloyan D. Georgiev, Maya Radeva-Ilieva, Stanila Stoeva, Iliya Zhelev |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-50468-7 |
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