Isolation, analysis and in vitro assessment of CYP3A4 inhibition by methylxanthines extracted from Pu-erh and Bancha tea leaves

Abstract Methylxanthines, purine alkaloids found in plants, are found in beverages (coffee, tea, cocoa) and foods (chocolate and other cocoa-containing foods) commonly consumed worldwide. Members of this family include caffeine, theophylline and theobromine. Methylxanthines have a variety of pharmac...

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Bibliographic Details
Main Authors: Kaloyan D. Georgiev, Maya Radeva-Ilieva, Stanila Stoeva, Iliya Zhelev
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-50468-7