WJMSC‐derived small extracellular vesicle enhance T cell suppression through PD‐L1

WJMSC‐derived small extracellular vesicle enhance T cell suppression through PD‐L1

Abstract Both mesenchymal stem cells (MSCs) and their corresponding small extracellular vesicles (sEVs, commonly referred to as exosomes) share similar immunomodulatory properties that are potentially beneficial for the treatment of acute graft versus host disease (aGvHD). We report that clinical gr...

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Bibliographic Details
Main Authors: Meizhang Li, Rupal Soder, Sunil Abhyankar, Haitham Abdelhakim, Mitchell W. Braun, Camille V. Trinidad, Harsh B. Pathak, Ziyan Pessetto, Clayton Deighan, Siddhartha Ganguly, Buddhadeb Dawn, Joseph McGuirk, Neil Dunavin, Andrew K. Godwin
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Journal of Extracellular Vesicles
Subjects:
acute graft‐versus‐host disease
PD‐L1
small extracellular vesicles
T cell receptor
Wharton's Jelly‐derived mesenchymal stem cells
Online Access:https://doi.org/10.1002/jev2.12067

Internet

https://doi.org/10.1002/jev2.12067

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