Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8

Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8

Summary: The transcription factors (TFs) that regulate inducible genes in activated neutrophils are not yet completely characterized. Herein, we show that the genomic distribution of the histone modification H3K27Ac, as well as PU.1 and C/EBPβ, two myeloid-lineage-determining TFs (LDTFs), significan...

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Bibliographic Details
Main Authors: Nicola Tamassia, Francisco Bianchetto-Aguilera, Sara Gasperini, Sara Polletti, Elisa Gardiman, Renato Ostuni, Gioacchino Natoli, Marco A. Cassatella
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
neutrophil, Transcription Factor, OCT2, PU.1, C/EBPβ, TLR8, H3K27Ac
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004824

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http://www.sciencedirect.com/science/article/pii/S2211124721004824

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