Biomimetic Mineralization Promotes Viability and Differentiation of Human Mesenchymal Stem Cells in a Perfusion Bioreactor

Biomimetic Mineralization Promotes Viability and Differentiation of Human Mesenchymal Stem Cells in a Perfusion Bioreactor

In bone tissue engineering, the design of 3D systems capable of recreating composition, architecture and micromechanical environment of the native extracellular matrix (ECM) is still a challenge. While perfusion bioreactors have been proposed as potential tool to apply biomechanical stimuli, its use...

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Bibliographic Details
Main Authors: Gloria Belén Ramírez-Rodríguez, Ana Rita Pereira, Marietta Hermann, Jan Hansmann, José Manuel Delgado-López, Simone Sprio, Anna Tampieri, Monica Sandri
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
scaffold
perfusion bioreactor
collagen
apatite nanoparticles
magnesium
human mesenchymal stem cell
Online Access:https://www.mdpi.com/1422-0067/22/3/1447

Internet

https://www.mdpi.com/1422-0067/22/3/1447

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