Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population

Werner syndrome (WS) is a premature aging disease caused by a mutation in the WRN gene. The gene was identified in 1996 and its product acts as a DNA helicase and exonuclease. Some specific WRN polymorphic variants were associated with increased risk for cardiovascular diseases. The identification o...

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Bibliographic Details
Main Authors: M.A.C. Smith, M.D.A. Silva, L.Q. Araujo, L.R. Ramos, R.W. Labio, R.R. Burbano, C.A. Peres, S.B. Andreoli, S.L.M. Payão, M.S. Cendoroglo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700008