PrtA immunization fails to protect against pulmonary and invasive infection by Streptococcus pneumoniae

PrtA immunization fails to protect against pulmonary and invasive infection by Streptococcus pneumoniae

Abstract Background Streptococcus pneumoniae is a respiratory pathogen causing severe lung infection that may lead to complications such as bacteremia. Current polysaccharide vaccines have limited serotype coverage and therefore cannot provide maximal and long-term protection. Global efforts are bei...

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Bibliographic Details
Main Authors: Chen-Fang Hsu, Chen-Hao Hsiao, Shun-Fu Tseng, Jian-Ru Chen, Yu-Jou Liao, Sy-Jou Chen, Chin-Sheng Lin, Huey-Kang Sytwu, Yi-Ping Chuang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Respiratory Research
Subjects:
Streptococcus pneumoniae
IL-17A
PrtA
Curdlan
Online Access:http://link.springer.com/article/10.1186/s12931-018-0895-8

Internet

http://link.springer.com/article/10.1186/s12931-018-0895-8

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