Understanding the cellular mode of action of vernakalant using a computational model: answers and new questions

Vernakalant is a new antiarrhythmic agent for the treatment of atrial fibrillation. While it has proven to be effective in a large share of patients in clinical studies, its underlying mode of action is not fully understood. In this work, we aim to link experimental data from the subcellular, tissue...

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Bibliographic Details
Main Authors: Loewe Axel, Xu Yan, Scholz Eberhard P., Dössel Olaf, Seemann Gunnar
Format: Article
Language:English
Published: De Gruyter 2015-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:http://www.degruyter.com/view/j/cdbme.2015.1.issue-1/cdbme-2015-0101/cdbme-2015-0101.xml?format=INT