Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice.

Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice.

Resveratrol is often described as a promising therapeutic molecule for numerous diseases, especially in metabolic and neurodegenerative disorders. While the mechanism of action is still debated, an increasing literature reports that resveratrol regulates the mitochondrial respiratory chain function....

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Bibliographic Details
Main Authors: Naïg Gueguen, Valérie Desquiret-Dumas, Géraldine Leman, Stéphanie Chupin, Stéphanie Baron, Valérie Nivet-Antoine, Emilie Vessières, Audrey Ayer, Daniel Henrion, Guy Lenaers, Pascal Reynier, Vincent Procaccio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4694087?pdf=render

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http://europepmc.org/articles/PMC4694087?pdf=render

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