T Cell Repertoire and Inflammatory Bowel Disease

The diversity of the T cell receptor repertoire is generated through rearrangement of the variable, junctional and constant region genes. Selection processes in the thymus and periphery serve to eliminate self-reacting T cells, thereby preventing autoimmune disease. The possibility that inflammatory...

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Bibliographic Details
Main Authors: Kenneth Croitoru, David KH Wong, Maria E Baca-Estrada
Format: Article
Language:English
Published: Hindawi Limited 1996-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1996/764732