Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor.
Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG-containing DNA response elements in a methylation-dependent manner. The EBV genome undergoes a biphasic methylation cycle; i...
Main Authors: | Kirsty Flower, David Thomas, James Heather, Sharada Ramasubramanyan, Susan Jones, Alison J Sinclair |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3191170?pdf=render |
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