Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor.

Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor.

Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG-containing DNA response elements in a methylation-dependent manner. The EBV genome undergoes a biphasic methylation cycle; i...

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Bibliographic Details
Main Authors: Kirsty Flower, David Thomas, James Heather, Sharada Ramasubramanyan, Susan Jones, Alison J Sinclair
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3191170?pdf=render

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http://europepmc.org/articles/PMC3191170?pdf=render

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