Lipophilic fractions from the marine sponge Halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4+ T cells

Lipophilic fractions from the marine sponge Halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4+ T cells

Context: Halichondria (Halichondriidae) marine sponges contain components possessing various biological activities, but immunomodulation is not among the ones reported. Objective: This study evaluated the immunomodulatory effects of fractions/compounds from Halichondria sitiens Schmidt. Materials an...

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Bibliographic Details
Main Authors: Xiaxia Di, Jon T. Oskarsson, Sesselja Omarsdottir, Jona Freysdottir, Ingibjorg Hardardottir
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
immunomodulation
anti-inflammatory effects
natural products
Online Access:http://dx.doi.org/10.1080/13880209.2017.1373832

Internet

http://dx.doi.org/10.1080/13880209.2017.1373832

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