Immunoinformatic Docking Approach for the Analysis of KIR3DL1/HLA-B Interaction

KIR3DL1 is among the most interesting receptors studied, within the killer immunoglobulin receptor (KIR) family. Human leukocyte antigen (HLA) class I Bw4 epitope inhibits strongly Natural Killer (NK) cell’s activity through interaction with KIR3DL1 receptor, while Bw6 generally does not. This inter...

Full description

Bibliographic Details
Main Authors: Alba Grifoni, Carla Montesano, Atanas Patronov, Vittorio Colizzi, Massimo Amicosante
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/283805