Constructing and Characterizing Bacteriophage Libraries for Phage Therapy of Human Infections

Constructing and Characterizing Bacteriophage Libraries for Phage Therapy of Human Infections

Phage therapy requires libraries of well-characterized phages. Here we describe the generation of phage libraries for three target species: Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae. The basic phage characteristics on the isolation host, sequence analysis, growth properties,...

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Bibliographic Details
Main Authors: Shelley B. Gibson, Sabrina I. Green, Carmen Gu Liu, Keiko C. Salazar, Justin R. Clark, Austen L. Terwilliger, Heidi B. Kaplan, Anthony W. Maresso, Barbara W. Trautner, Robert F. Ramig
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
phage libraries
phage therapy
host range
phage characteristics
killing spectrum
human infection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02537/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02537/full

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