Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis

Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis

Obesity is correlated with increased incidence of breast cancer metastasis; however, the mechanisms underlying how obesity promotes metastasis are unclear. In a diet-induced obese mouse model, obesity enhanced lung metastasis in both the presence and absence of primary mammary tumors and increased r...

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Bibliographic Details
Main Authors: Lauren E. Hillers-Ziemer, Abbey E. Williams, Amanda Janquart, Caitlin Grogan, Victoria Thompson, Adriana Sanchez, Lisa M. Arendt
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
obesity
breast cancer
metastasis
macrophages
collagen
lung fibroblasts
Online Access:https://www.mdpi.com/2072-6694/13/5/1005

Internet

https://www.mdpi.com/2072-6694/13/5/1005

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