Functional polymorphism of IL-1 alpha and its potential role in obesity in humans and mice.

Proinflammatory cytokines secreted from adipose tissue contribute to the morbidity associated with obesity. IL-1α is one of the proinflammatory cytokines; however, it has not been clarified whether IL-1α may also cause obesity. In this study, we investigated whether polymorphisms in IL-1α contribute...

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Bibliographic Details
Main Authors: Jae-Young Um, Hong-Kun Rim, Su-Jin Kim, Hye-Lin Kim, Seung-Heon Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3246492?pdf=render