DNA repair gene XRCC7 G6721T variant and susceptibility to colorectal cancer
Background: The human XRCC7 (MIM: 600899) is a DNA double-strand break repair gene, involved in non-homologous end joining (NHEJ). Polymorphism G6721T (rs7003908) is located in the intron 8 of the XRCC7. This polymorphism may regulate splicing and cause mRNA instability. Aim: The aim of the present...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2016-10-01
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Series: | Egyptian Journal of Medical Human Genetics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1110863016000239 |